Eliminating SCID row: new approaches to SCID
نویسندگان
چکیده
منابع مشابه
Differentiation of uterine natural killer cells in pregnant SCID (scid/scid) mice.
To determine whether functional T- and B-cells can affect differentiation and/or proliferation of uterine natural killer (uNK) cells, their numbers in SCID mice (genotype, C.B.-17/Icr-scid/scid) were compared with those of control mice (genotype, C.B.-17/Icr-+/+) on days 8, 12 and 16 of pregnancy. Using biotinylated-Dolichos biflorus agglutinin (DBA) lectin staining, uNK cells can be readily cl...
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The tumor-suppressing phenotype of p53 is thought to be due to its accumulation in response to DNA damage and resultant cell cycle arrest or apoptosis. scid/scid mice are defective in DNA double-strand break repair due to a mutation in DNA-dependent protein kinase (DNAPK). Treatment of scid/scid mice with gamma radiation or N-ethyl-N-nitrosourea resulted in approximately 86% incidence of T-cell...
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ژورنال
عنوان ژورنال: Hematology
سال: 2014
ISSN: 1520-4391,1520-4383
DOI: 10.1182/asheducation-2014.1.475